I have considered the Camry Hybrid for my mother. She currently has a 2002 Camry LE 4cyl which has been great. She loves her car, but I'm wondering how the Toyota Hybrids do if they sit for large amounts of time. She does not have a garage where she lives in Atlanta, so putting a trickle charger on the accessory battery will not work. Her current Camry is 4 1/2 years old and has only 27,000 miles on it. She doesn't drive much. My Prius takes a while to get back to its normal mileage after it sits for a week, about 2 days of commuting or 1 good day of driving all over the place.
Anyway, I find the Prius more comfortable than the Camry. Mom has driven the Prius and loved it, but would prefer to be in the Camry.
I like the Highlander Hybrid and I am able to get the city numbers out of it quite easily. I have driven one for a day and was happy with it. I'm curious to see how the Sienna will do. Maybe Toyota can come up with a super HSD setup for their trucks that will rival their gasoline powered sisters.